A highlight from an article posing a very interesting hypothesis in the online journal Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. Is it the carb density of modern foods that is the problem?
The present hypothesis suggests that in parallel with the bacterial effects of sugars on dental and periodontal health, acellular flours, sugars, and processed foods produce an inflammatory microbiota via the upper gastrointestinal tract, with fat able to effect a “double hit” by increasing systemic absorption of lipopolysaccharide. This model is consistent with a broad spectrum of reported dietary phenomena. A diet of grain-free whole foods with carbohydrate from cellular tubers, leaves, and fruits may produce a gastrointestinal microbiota consistent with our evolutionary condition, potentially explaining the exceptional macronutrient-independent metabolic health of non-Westernized populations, and the apparent efficacy of the modern “Paleolithic” diet on satiety and metabolism.
This is just a hypothesis, but it is an intriguing one! You can download the full text (PDF) or stay tuned. I’ll be posting more on this later this week.